Molecular Immunotoxicology

Molecular Immunotoxicology PDF
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Author: Emanuela Corsini
Publisher: John Wiley & Sons
ISBN: 3527335196
Size: 10.78 MB
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Category : Science
Languages : en
Pages : 352
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The first comprehensive reference on immunotoxicology using analyses based on molecular effects rather than on animal models. Following an introduction to immune system pathways and toxicity mechanisms from a systemic perspective, the main part of the book surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.


Experimental Immunotoxicology

Experimental Immunotoxicology PDF
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Author: Ralph J. Smialowicz
Publisher: CRC Press
ISBN:
Size: 54.14 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 487
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Immunotoxicology has emerged as a vital and expanding discipline over the past several years. Although the field of human immunotoxicology is arguably still in its infancy, a number of animal model systems have been well established and validated. Experimental Immunotoxicology provides an update on the recent advances in the field as it relates to animals and provokes discussion on approaches to the evaluation of human immunotoxicology. It is an important reference source for professionals in immunology and toxicology. The book begins with an overview of the mammalian immune system and covers the important role played by animal host susceptibility models. It also gives an update on immunotoxicolgy in sub-human primates. Vulnerability of bone marrow and the consequences of damage to immune function as well as chemical-induced immunosuppression as a consequence of exposure to chemicals are covered. Most of the chapters are organized to include a description of the profile of immunotoxicity, mechanisms of immunotoxicity, species comparisons and research needs.


Index Medicus

Index Medicus PDF
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Author:
Publisher:
ISBN:
Size: 39.93 MB
Format: PDF, Mobi
Category : Medicine
Languages : en
Pages :
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Nih Immunotoxicology Workshop

NIH Immunotoxicology Workshop PDF
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Author:
Publisher:
ISBN:
Size: 30.58 MB
Format: PDF, Docs
Category : Immunologic diseases
Languages : en
Pages : 420
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Principles And Methods Of Immunotoxicology

Principles and Methods of Immunotoxicology PDF
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Author: Jacques Descotes
Publisher: Elsevier
ISBN: 9780080472997
Size: 31.15 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 400
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This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.


Immunotoxicology And Immunopharmacology

Immunotoxicology And Immunopharmacology PDF
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Author: H Dean Jack
Publisher: CRC Press
ISBN: 9780781702195
Size: 25.19 MB
Format: PDF
Category : Medical
Languages : en
Pages : 761
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The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.


Encyclopedia Of Molecular Biology And Molecular Medicine Heart Failure Genetic Basis Of To Mammalian Genome

Encyclopedia of Molecular Biology and Molecular Medicine  Heart Failure  Genetic Basis of to Mammalian Genome PDF
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Author: Robert A. Meyers
Publisher: Wiley-Blackwell
ISBN: 9783527284733
Size: 44.65 MB
Format: PDF
Category : Science
Languages : en
Pages : 523
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This six volume Encyclopedia is the most comprehensive, detailed treatment of molecular biology and molecular medicine available today! The Encyclopedia provides a single-source library of molecular genetics and the molecular basis of life, with a focus on molecular medicine. Genetic screening, gene therapy, structural biology, and the technology and findings of the Human Genome Project are discussed in detail. The articles that comprise the set are designed as self-contained treatments. Each of the nearly 300 articles begins with an outline and a key word section which includes definitions. These features assist the scientist or student who is unfamiliar with a specific subject area. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, these definitions enable readers to understand articles without referring to a dictionary, textbook, or other reference.


Encyclopedia Of Molecular Biology And Molecular Medicine

Encyclopedia of Molecular Biology and Molecular Medicine PDF
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Author: Robert A. Meyers
Publisher: Wiley-Blackwell
ISBN: 9783527284788
Size: 71.78 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 29
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The most comprehensive, detailed, one-stop reference to molecular biology and molecular medicine today, this six-volume encyclopedia comprises nearly 300 self-contained and clearly written articles on genetic screening, gene therapy, structural biology, and the technology and findings of the Human Genome Project.


Introduction To Immunotoxicology

Introduction To Immunotoxicology PDF
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Author: Jacques Descotes
Publisher: CRC Press
ISBN: 9780748403073
Size: 72.71 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 183
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This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.


Immunotoxicity Of Metals And Immunotoxicology

Immunotoxicity of Metals and Immunotoxicology PDF
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Author: International Program on Chemical Safety
Publisher: Springer
ISBN:
Size: 45.10 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 317
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Considerable scientific and political interest has been expressed, parallelling public concern about the effects of chemicals on the immune system and the implications of those effects for health. Coupled with speculation about the magnitude and extent of the problem is discussion of needs for predictive testing and regulatory control measures. The first international seminar on the immunological system as a target for toxic damage was held in Luxembourg in 1984. It was organized by the International Programme on Chemical Safety (United Nations Environment Programme-International Labour Office World Health Organization) and the Commission of the European Communities with the support of the US Environmental Protection Agency and the National Institute of Environmental Health Sciences (USA) and the participation of the International Society of Immunopharmacology. In view of the perceived importance of imrnunotoxicity, it was considered necessary to organize a follow-up meeting. Thus, an international workshop on the immunotoxicity of metals and immuno toxicology was held in Hanover, Federal Republic of Germany, on 6-10 November 1989.