Intermediate Filaments

Intermediate Filaments PDF
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Author: Harald Herrmann
Publisher: Springer Science & Business Media
ISBN: 9780306458545
Size: 63.37 MB
Format: PDF
Category : Science
Languages : en
Pages : 622
View: 5984

This text looks at subcellular chemistry, particularly at intermediate filaments. Topics include fish intermediate filament proteins in structure, evolution, and function, and lessons from keratin transgenic and knockout mice.


Intermediate Filaments

Intermediate Filaments PDF
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Author: P. Traub
Publisher: Springer Science & Business Media
ISBN: 3642702309
Size: 67.91 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 266
View: 1371

Research on cytoskeletal elements of eukaryotic cells has been expand ing explosively during the past 5 to 10 years. Due largely to the employment of electron and immunofluorescent microscopy, significant results have been obtained which have provided interesting new insights into the dynamics of nucleated cells at the structural, physiological, as well as developmental levels. While a substantial amount of knowledge has accumulated on the function of microfilaments and microtubules, the roles of the third major class of cytoskeletal structures in vertebrate cells, the intermediate filaments, have largely resisted clarification. The investigation of cultured cells and of tissues from various developmental stages has furnished a host of information on the inter-and intracellular distribution of the different types of intermediate filaments and led to the contention that they have a structural and organizing function in the cytoplasm of vertebrate cells. However, the results of recent experimen that vertebrate cells can function perfectly in the tation have shown complete absence of cytoplasmically extended intermediate filament meshworks. It is legitimate to suppose, therefore, that their function in vertebrate cells is much more subtle and complex than generally presumed. Our interest in the structure and function of intermediate filament proteins was initiated approximately 7 years ago while working on the regulation of macromolecular synthesis in picornavirus-infected mam malian cells. In attempts to demonstrate virus-induced changes in the nuclear protein components of the host cells, the nonionic detergent extraction method was used to purify nuclei.


Intermediate Filament Cytoskeleton

Intermediate Filament Cytoskeleton PDF
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Author: M. Bishr Omary
Publisher: Gulf Professional Publishing
ISBN: 9780125641739
Size: 53.95 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 886
View: 510

Intermediate filaments are a large family of proteins that are the cytoskeletal elements involved in a number of skin, liver, neuromuscular, cardiac, eye and hair diseases. Intermediate filament genes are regulated in a tissue-and cell type-specific manner and their polymerized protein products protects the cells and tissue they are part of against a variety of mechanical and nonmechanical stresses. This book provides a comprehensive resource of methodology essentials, describing a variety of essential tools and assays for studying intermediate filaments. The book provides user-friendly advice and protocols covering all aspects of intermediate filaments including protein isolation and structure, protein and gene regulation, relationship to disease and apoptosis, and associated proteins. Both mammalian and non-mammalian systems and animal models are covered, making this book a must-have for any investigator wishing to study IF genes or their protein products. * Covers intermediate filaments from crystallography, protein chemistry, cell and molecular biology, microrheology, gene regulation, to animal models and human disease * Practical and user-friendly with detailed "how-to-protocols and "tricks of the trade" * Includes detailed tables of useful reagents, vendors and web links


Intermediate Filaments

Intermediate Filaments PDF
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Author: Jesus Paramio
Publisher: Springer Science & Business Media
ISBN: 0387337814
Size: 33.96 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 150
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Intermediate Filaments focuses on desmin and other intermediate filaments in disease and health. This new volume will serve as a resource for graduate students and researchers in the field.


Immunological Biochemical And Morphological Studies On Intermediate Filaments

Immunological  Biochemical and Morphological Studies on Intermediate Filaments PDF
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Author: Uno Kjörell
Publisher:
ISBN:
Size: 63.31 MB
Format: PDF
Category : Cytoplasmic filaments
Languages : en
Pages : 41
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Intermediate Filaments

Intermediate Filaments PDF
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Author: Eugenia Wang
Publisher:
ISBN: 9780897663052
Size: 71.87 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 832
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Desmin Intermediate Filaments Mechanical And Biological Role In Skeletal Muscle

Desmin Intermediate Filaments  Mechanical and Biological Role in Skeletal Muscle PDF
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Author: Michelle Geré Palmisano
Publisher:
ISBN:
Size: 80.34 MB
Format: PDF
Category :
Languages : en
Pages : 218
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The Role Of The Desmin Intermediate Filaments In Muscle Injury

The Role of the Desmin Intermediate Filaments in Muscle Injury PDF
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Author: Michel Sam
Publisher:
ISBN:
Size: 69.94 MB
Format: PDF, Mobi
Category :
Languages : en
Pages : 234
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Impact Of Bis Beta Chloroethyl Sulfide On Keratin Protein And Intermediate Filaments In Cultured Keratinocytes As Indicated By Monoclonal Antibody Binding

IMPACT OF BIS  BETA CHLOROETHYL  SULFIDE ON KERATIN PROTEIN AND INTERMEDIATE FILAMENTS IN CULTURED KERATINOCYTES AS INDICATED BY MONOCLONAL ANTIBODY BINDING  PDF
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Author: BETTY J. LOCEY
Publisher:
ISBN:
Size: 69.34 MB
Format: PDF, Kindle
Category : Keratinocytes
Languages : en
Pages : 168
View: 1862

protein.