Guidebook To The Cytoskeletal And Motor Proteins

Guidebook to the Cytoskeletal and Motor Proteins PDF
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Author: Thomas Kreis
Publisher: Sambrook and Tooze Publication at Oxford University Press
ISBN: 9780198599579
Size: 49.37 MB
Format: PDF
Category : Medical
Languages : en
Pages : 551
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Since the first edition, many new and important discoveries have been made in this expanding area of research. This updated edition details all that is currently known about the proteins involved in the microfilament, microtubule and intermediate filament systems in cells and their roles intension resistance and motor function. Biochemists will find this book particularly useful as will physiologists and biologists in fields in which these proteins are involved, such as neuromuscular research.

Annual Plant Reviews The Plant Cytoskeleton In Cell Differentiation And Development

Annual Plant Reviews  The Plant Cytoskeleton in Cell Differentiation and Development PDF
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Author: Patrick J. Hussey
Publisher: John Wiley & Sons
ISBN: 1405147873
Size: 77.14 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 344
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Annual Plant Reviews, Volume 10 The cytoskeleton is a dynamic filamentous structure composed of at least actin and microtubule networks. Actin and microtubules are no different structurally from their animal and fungal counterparts. However, the strategies of cell differentiation and development in plants require this network to respond appropriately to plant-specific developmental cues and to environmental factors. This book views the cytoskeleton from different perspectives but, on the whole, as a network composed of structural and regulatory proteins controlled by internal and external stimuli that result in different aspects of cell differentiation. This is a volume for researchers and professionals in plant biochemistry, cell biology and genetics.

Connecting Beta2 Adrenergic Receptor To The Actin Cytoskeleton And Inhibiting Microtubule Polymerization Ebp50 Nherf Ilimaquinone And Op18 Stathmin

Connecting Beta2 adrenergic Receptor to the Actin Cytoskeleton and Inhibiting Microtubule Polymerization  EBP50 NHERF  Ilimaquinone  and Op18 stathmin PDF
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Author: Heather Winsome Deacon
Size: 29.13 MB
Format: PDF
Category : Biochemistry
Languages : en
Pages : 225
View: 1362

Both the actin and the microtubule cytoskeleton are involved in transporting transmembrane proteins through cells. Using fluorescent imaging of living cells, we have found that endocytosed beta2-adrenergic receptor enters membrane tubules that rapidly move along microtubules. Using epi-fluorescent and confocal microscopy, we have demonstrated that beta2-adrenergic receptor clustering, endocytosis, recycling, and entry into membrane tubules are sensitive to latrunculin. Using co-immunoprecipitation, we have discovered that EBP50/NHERF (50 kDa ERM-binding phosphoprotein/Na + -H + exchanger regulatory factor), a component of the apical actin cytoskeleton that binds to the beta2-adrenergic receptor in vitro , also binds to the beta2-adrenergic receptor in cells. This bound EBP50/NHERF is phosphorylated, and possibly exists as a homo-dimer in cells. Binding to EBP50/NHERF or a related protein--possibly in a larger complex that contains actin--may regulate beta2-adrenergic receptor trafficking in tissue culture cells. Microtubule arrays are established in cells by a number of stabilizing and destabilizing proteins. Microtubule associated proteins, or MAPs, are a class of microtubule stabilizing proteins. We identify a ~100 kDa factor that destabilizes microtubules by causing catastrophes in the presence of the drug, ilimaquinone. We also demonstrate that this factor is not a MAP. Op18 family members, which are also not MAPS, destabilize microtubules both by causing catastrophes and by sequestering tubulin subunits. Using video-enhanced DIC microscopy, we provide evidence that Op18 causes catastrophes at both ends of microtubules in vitro , indicating that Op8 disrupts protofilament packing. Furthermore, hydrodynamic analysis of Op18 in vitro and in vivo demonstrates that Op18 does not act as a microtubule sequestering protein in Xenopus egg extracts, but is found in a large complex of unknown composition in interphase extracts.

Heidelberger Jahrb Cher

Heidelberger Jahrb  cher PDF
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Author: Universitäts-Gesellschaft Heidelberg
Publisher: Springer-Verlag
ISBN: 3642793487
Size: 27.89 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : de
Pages : 381
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Inhaltsübersicht: Ernst G. Jung: Das maligne Melanom. - Karin Gorgas, Wilhelm Just: Zur Struktur und Funktion von Peroxisomen. - Hans Elsässer: Von der Frühgeschichte des Universums. - Kurt Egger: Acht Jahre Modellprojekt "PIASP" in Rwanda. - Frauke Gewecke: Kolumbus und (k)ein Ende. - Leonhard Emmerling: Bildnerei der Geisteskranken, Art Brut und Außenseiterkunst - Ansätze zu einer Begriffsklärung. - Günther Debon: Beim Blättern in den 'Sonetten an Orpheus'. - István Borzsák: Rückschau eines Taciteers. - Claude Lauriol: Die Hugenotten und die Philosophen von der Aufhebung des Edikts von Nantes zum Toleranzedikt (1685-1781). - Eberhard Demm: Alfred Weber und der Geist von Heidelberg. Ein Beitrag zur Mentalitätsgeschichte der Heidelberger Bildungselite. - Hans-Georg Gadamer: Laudatio für Jeanne Hersch (Karl-Jaspers-Preis). - Jeanne Hersch: Von der Wirkung einer "philosophia negativa" (Karl-Jaspers-Preis). - Peter König: Über einige Aspekte von Kants Tugendlehre. - Wolfgang Jaeger: 50 Jahre "Weiße Rose"--Eike Wolgast: Zum Gedenken an die durch die NS-Diktatur vertriebenen und entrechteten Dozenten der Ruperto Carola.

Guidebook To The Calcium Binding Proteins

Guidebook to the Calcium binding Proteins PDF
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Author: Marco R. Celio
Publisher: Oxford University Press
Size: 72.25 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 238
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Each entry includes data on isolation/identification, alternative names, genes and sequences, proteins, antibodies, and biological activities.

Cell Biology E Book

Cell Biology E Book PDF
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Author: Thomas D. Pollard
Publisher: Elsevier Health Sciences
ISBN: 1437700632
Size: 61.75 MB
Format: PDF
Category : Medical
Languages : en
Pages : 928
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A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It emphasizes that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The exquisite art program helps you to better visualize molecular structures. Covers essential concepts in a more efficient, reader-friendly manner than most other texts on this subject. Makes cell biology easier to understand by demonstrating how cellular structure, function, and dysfunction result from specific macromole¬cular interactions. Progresses logically from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. Helps you to visualize molecular structures and functions with over 1500 remarkable full-color illustrations that present physical structures to scale. Explains how molecular and cellular structures evolved in different organisms. Shows how molecular changes lead to the development of diseases through numerous Clinical Examples throughout. Includes STUDENT CONSULT access at no additional charge, enabling you to consult the textbook online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles—to help you see the connections between diverse disciplines · test your knowledge with multiple-choice review questions · and more! New keystone chapter on the origin and evolution of life on earth probably the best explanation of evolution for cell biologists available! Spectacular new artwork by gifted artist Graham Johnson of the Scripps Research Institute in San Diego. 200 new and 500 revised figures bring his keen insight to Cell Biology illustration and further aid the reader’s understanding. New chapters and sections on the most dynamic areas of cell biology - Organelles and membrane traffic by Jennifer Lippincott-Schwartz; RNA processing (including RNAi) by David Tollervey., updates on stem cells and DNA Repair. ,More readable than ever. Improved organization and an accessible new design increase the focus on understanding concepts and mechanisms. New guide to figures featuring specific organisms and specialized cells paired with a list of all of the figures showing these organisms. Permits easy review of cellular and molecular mechanisms. New glossary with one-stop definitions of over 1000 of the most important terms in cell biology.

Elastomeric Proteins

Elastomeric Proteins PDF
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Author: Peter R. Shewry
Publisher: Cambridge University Press
ISBN: 9781139438209
Size: 62.28 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages :
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This book was originally published in 2002. Elastic proteins occur in a wide range of biological systems where they have evolved to fulfil precise biological roles. The best known include proteins in vertebrate muscles and connective tissues, such as titin, elastin and fibrillin, and spider silks. However, other examples include byssus and abductin from bivalve molluscs, resilin from arthropods and gluten from wheat. Interest in elastomeric proteins has been high for several reasons. Firstly, their biological and medical significance, particularly in human disease. Secondly, the unusual properties of proteins such as spider silks provide opportunities to develop materials. Thirdly, the development of scanning probe microscopy makes it possible to study structures and biomechanical properties of these proteins at the single molecule level. This book will be of value to anyone with an interest in the various aspects of elastomeric proteins.

Guidebook To Cytokines And Their Receptors

Guidebook to Cytokines and Their Receptors PDF
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Author: Nicos Nicola
Publisher: Oxford University Press on Demand
Size: 25.72 MB
Format: PDF
Category : Cytokines
Languages : en
Pages : 261
View: 3717

The number of cytokines and related growth factors has increased dramatically in recent years to several dozen. This text provides a succinct reference manual for all known cytokines, growth factors, interleukins and lymphokines as well as their receptors.