Author: Wafik S. El-Deiry
Publisher: Springer Science & Business Media
ISBN: 159259851X
Size: 35.62 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 374
View: 5520
An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.
Get This Book
Author: U.S. Atomic Energy Commission. Oak Ridge Operations Office
Publisher:
ISBN:
Size: 64.47 MB
Format: PDF, Docs
Category : Animals--Radioactive contamination
Languages : en
Pages :
View: 4749
Get This Book
Author:
Publisher:
ISBN:
Size: 16.98 MB
Format: PDF, ePub
Category : Kidneys
Languages : en
Pages :
View: 6881
Get This Book
Author:
Publisher:
ISBN:
Size: 45.60 MB
Format: PDF, Docs
Category : Medicine
Languages : en
Pages :
View: 2779
Get This Book
Author: Roya Khosravi-Far
Publisher: Springer Science & Business Media
ISBN: 9781402065545
Size: 52.58 MB
Format: PDF
Category : Medical
Languages : en
Pages : 356
View: 1561
Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mechanisms involved in mediating and regulating PCD in cancer. It also provides a detailed indication of the utility of PCD in cancer therapy. The book features chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death.
Get This Book
Author: Edwin James Houston
Publisher:
ISBN:
Size: 73.16 MB
Format: PDF, Mobi
Category : Electric engineering
Languages : en
Pages : 562
View: 4148
Get This Book
Author:
Publisher:
ISBN:
Size: 73.41 MB
Format: PDF, Mobi
Category : Kokomo (Ind.)
Languages : en
Pages :
View: 3072
Get This Book
Author: Laura Barnett
Publisher: Routledge
ISBN: 1134117019
Size: 76.90 MB
Format: PDF, ePub
Category : Family & Relationships
Languages : en
Pages : 256
View: 6810
Although it is a natural and inescapable part of life, death is a subject that is often neglected in psychotherapeutic literature and training. In When Death Enters the Therapeutic Space Laura Barnett and her contributors offer us insights into working with mortality in the therapeutic encounter. Taking an existential perspective, the book brings together a variety of client groups, all of whom have experienced a confrontation with mortality, and encourages the reader to engage with and reflect upon the subject of death. Although this may initially evoke anxiety and distress, Barnett and her contributors introduce the reader to the 'vitality of death' (Koestenbaum): an energy and focus that can come from confronting our greatest fears and anxieties, including the anxiety aroused by our own mortality. Topics covered include: philosophical roots and principal approaches to existential therapy health related issues including cancer, HIV and Intensive Care surviving violent trauma creating a safe space for the client short prognosis and palliative care bereavement. When Death Enters the Therapeutic Space presents therapists with an understanding of what it means to experience such traumas and prepares them for helping the client. It will be useful for trainee counsellors and experienced therapists alike.
